Active hemoglobin complex with high oxygen-carrying capacity applied in in-vitro & in-vivo processes

A new type of hemoglobin suitable to work as a potent oxygen carrier

The company M bioserviceS – together with their German partner Biophyll - are owning and further developing a novel hemoglobin complex ActoHem – Active Hemoglobin Complex for various in-vitro & in-vivo application areas. There are many commercially available bovine hemoglobins but this hemoglobin complex is characterised by a high oxygen carrying capacity, purity, safety and functionality which can be used in many more application areas for the first time:

·      Human erythrocytes replacement in cell culture media used during transport of organs for perfusion

·      Active ingredient in wound bandages (especially for chronic wounds)

·      Cell culture additive for better oxygenation

·      Ingredient for biological coating of cell culture plastics

·      Veterinary applications - contributing to joints healing of pet animals

·      Preventing hair loss

·      In any other areas where an improved oxygen supply is required

Technical data

The active hemoglobin complex is manufactured from calves red blood cells sourced in Tyrol, Austria - a region free of most bovine diseases as well as of BSE. It has been harvested from locally and organically raised animals with proven traceability and carefully monitored health records. The red blood cells are lysed and the hemoglobin is then obtained via centrifugation and filtration steps.

Key benefits

·      The presented active hemoglobin can be produced with high purity, without particulate matter and with a very low amount of methemoglobin (≤ 10% according to specifications the sheet). With the high functionality regarding oxygen carrying capacity, the hemoglobin can be used as a starting material for various products.

·       Longer shelf life than human erythrocytes currently in use 8 months at < - 15°C

·       Maintains biological activity over a long period of time: 8 months at < - 15°C

·       Easily commercially available at low cost

·      Almost unlimited supply possible

·       Easy to manufacture

·      Can be used for manufacturing of patented micro-particles with advantageous properties

·      Can be stored frozen without adverse effects

·      A safe and effective starting material for the manufacturing of laboratory reagents, medical devices up to Pharmaceuticals

The team and developers are looking for partner companies who need specific oxygen carriers and are interested in technical cooperations with no need for financial input, commercial agreements or license agreements.