Biocompatible, secure and sensitive fluorescent probes, especially significant for optical applications due to their bright and pure colours

The product 4nDOTS™ is particularly significant for optical applications owing to its bright, pure colours along with its ability to emit all colours of the visible VIS up to the near infrared NIR spectrum. Examples include biomedical imaging, sensors, solid-state lighting, displays and photovoltaics.

The small hydrodynamic radius of the product makes it suitable for various biomedical applications. The nanoprobes are fully biocompatible due to their aqueous medium and their controlled pH. This unique feature makes them ideally suited for the use in bioimaging applications in cellular and sub-cellular imaging and detection, including ex vivo, in vitro long-term life cell imaging and in vivo animal targeting.

At present, fluorescence based biosensors depend on organic dyes with a broad spectral width, which limits their effectiveness to a small number of colours and shorter lifetimes to tag the agents. 4nDOTS™ can emit in the whole spectrum, the nanoprobes are brighter and substantially eliminate photo bleaching over time thus proving them superior to traditional organic dyes used in biomedical applications.

Being zero dimensional, quantum dots have a sharper density of states than higher-dimensional structures. Their small size also means that electrons do not have to travel as far as with larger particles, thus electronic devices can operate faster. Examples of applications taking advantage of these unique electronic properties include transistors, photovoltaics, ultrafast all-optical switches and logic gates, and quantum computing, among many others.

• Secure: In strong contrast to 4nDOTS™ , commonly used organic dyes require fixing the cells and thus do not allow time studies over a longer period with the same cell cultures as it is possible using the offered biocompatible nanoprobes.
• Sensitive: 4nDOTS™ eliminate photo bleaching over time thus proving them superior to traditional organic dyes used in biomedical applications. They are fully biocompatible due to their aqueous medium and their controlled pH.
• Reproducible: 4nDOTS™ consist of a well-defined number of atoms and thus allow a quantitative determination of the substance to be determined which connects to each 4nDOT™.
• emits the whole spectrum
• bright emissions of various wave-lengths
• narrow emission spectra
• high purity

With 4n , the company PHORNANO Holding GmbH offers predefined as well as customised and specifically developed products for use in research and industry and is ready to accompany the upscale together with its partners and clients.